TABLE 2.

Results of GEE analysis with the daily total scores on the Daily Record of Severity of Problems (DRSP) as dependent variables and different PMS group, time and time X group interaction as independent variables.

Group variables	Time			Group			Time X diagnosis			Daily mean (SE)
	X2	df	P	X2	df	p	X2	df	p	No	Yes
ACOG	362.77	27	<0.001	2.58	1	0.108	187.64	27	<0.001	31.37 (1.77)	34.87 (1.45)
PMS	605.89	27	<0.001	5.33	1	0.021	103.95	27	<0.001	30.60 (1.37)	36.32 (1.64)
PeriMS	822.05	27	<0.001	81.05	1	<0.001	288.63	27	<0.001	27.72 (0.44)	40.00 (1.30)
MCAS	732.76	27	<0.001	180.56	1	<0.001	285.67	27	<0.001	28.58 (0.54)	42.71 (0.95)

ACOG = Premenstrual syndrome diagnosis according to American College of Obstetricians and Gynecologists (ACOG) criteria. PMS = Subjects who scored ≥70 of total DRSP score during day 24–28 of menstrual cycle and there is a difference of at least 30% in DRSP scores between pre (late luteal phase day 24–28) and post (mid follicular day 6–10) menstrual phases. PeriMS = peri-menstrual syndrome. MCAS = menstrual cycle-associated symptoms.