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miRNA biogenesis and nomenclature. The figure illustrates the key steps in miRNAs biogenetic canonical pathways. The light orange boxes indicate the step, the green boxes the key enzyme/enzyme complexes involved in the process, and the light blue boxes the miRNAs and miRNAs precursor nomenclature and specifications (according to Griffiths-Jones et al., 2006). RNA Pol II, RNA polymerase II; EXP5, exportin 5; RISC, RNA-induced silencing complex; AGO-2, argonaute-2 protein.
