Table 2.
Odds of vascular disease in patients with psoriasis compared with matched patients without psoriasis, stratified by sex
| Women | Psoriasis, n (%) |
No psoriasis, n (%) |
OR (95% CI) |
Adjusted OR (95% CI)⁎ |
|---|---|---|---|---|
| n = 10,557 | n = 31,671 | |||
| Atherosclerotic CVD | ||||
| Any atherosclerosis | 191 (1.8) | 221 (0.7) | 2.6 (2.1-3.2) | 1.4 (1.1-1.8) |
| Coronary artery disease | 89 (0.8) | 93 (0.3) | 2.9 (2.1-3.9) | 1.2 (0.8-1.8) |
| Acute myocardial infarction | 16 (0.2) | 17 (0.05) | 1.9 (1.3-2.9) | 1.3 (0.6-2.9) |
| Cerebrovascular disease | 71 (0.7) | 97 (0.3) | 2.3 (1.6-3.0) | 1.5 (1.0-2.0) |
| Acute ischemic stroke | 27 (0.3) | 37 (0.1) | 2.2 (1.3-3.6) | 1.7 (0.9-2.9) |
| Peripheral artery disease | 40 (0.4) | 40 (0.1) | 3.0 (1.9-4.7) | 1.9 (1.1-3.2) |
| Venous thromboembolism | ||||
| Any venous thromboembolism | 94 (0.9) | 142 (0.5) | 2.0 (1.5-2.6) | 1.3 (0.9-1.8) |
| Deep vein thrombosis | 51 (0.5) | 73 (0.2) | 2.1 (1.5-3.0) | 1.8 (1.2-2.7) |
| Pulmonary embolism | 59 (0.6) | 88 (0.3) | 2.0 (1.4-2.8) | 1.2 (0.8-1.7) |
| Men | n = 7796 | n = 23,388 | ||
| Atherosclerotic CVD | ||||
| Any atherosclerosis | 205 (2.6) | 529 (2.3) | 1.2 (0.9-1.4) | 0.9 (0.8-1.10) |
| Coronary artery disease | 142 (1.8) | 329 (1.4) | 1.3 (1.1-1.6) | 1.0 (0.8-1.2) |
| Acute myocardial infarction | 51 (0.7) | 91 (0.4) | 1.7 (1.2-2.4) | 1.4 (1.0-1.9) |
| Cerebrovascular disease | 50 (0.6) | 152 (0.7) | 1.0 (0.7-1.4) | 0.9 (0.6-1.2) |
| Acute ischemic stroke | 23 (0.3) | 66 (0.3) | 1.0 (0.7-1.7) | 1.0 (0.6-1.6) |
| Peripheral artery disease | 31 (0.3) | 72 (0.3) | 0.9 (0.5-1.4) | 0.8 (0.5-1.3) |
| Venous thromboembolism | ||||
| Any venous thromboembolism | 83 (1.1) | 261 (1.1) | 0.9 (0.7-1.2) | 0.9 (0.7-1.2) |
| Deep vein thrombosis | 51 (0.7) | 141 (0.6) | 1.1 (0.8-1.5) | 1.0 (0.7-1.4) |
| Pulmonary embolism | 42 (0.5) | 153 (0.7) | 0.8 (0.6-1.2) | 0.8 (0.6-1.1) |
CI, confidence interval; CVD, cardiovascular disease; OR, odds ratio
OR adjusted for age, race/ethnicity, and year of hospital admission.
⁎
Multivariable model adjusted for age, race/ethnicity, obesity, hypertension, diabetes, hyperlipidemia, tobacco use, and year of hospital admission.