Table 1.
Multivariable Analysis of STAB1 and Clinical Variables in TCGA and GSE6891 Cohort
| Overall Survival Covariate | TCGA Dataset |
GSE6891 Dataset |
||
|---|---|---|---|---|
| HR (95% CI) | p Value | HR (95% CI) | p Value | |
| STAB1 | 1.98 (1.01−3.03) | 0.0473 | 0.43 (1.05−2.24) | 0.027511 |
| Age | 2.44 (1.15−3.62) | 0.0147 | NA | NA |
| DNMT3A | 2.20 (1.07−3.50) | 0.028 | NA | NA |
| RUNX1 | 2.04 (1.03−5.37) | 0.0417 | NA | NA |
| FLT3-ITD | 1.59 (0.89−3.07) | 0.1124 | 0.57 (1.20−2.60) | 0.004015 |
| MT-CYB | 1.33 (0.66−8.75) | 0.185 | NA | NA |
| WT1 | 1.16 (0.66−5.02) | 0.2461 | NA | NA |
| IDH2 | 0.47 (0.56−2.59) | 0.638 | −0.05 (0.49−1.83) | 0.879925 |
| NPM1 | −0.05 (0.53−1.85) | 0.963 | −0.45 (0.43−0.94) | 0.022836 |
| IDH1 | −1.28 (0.16−1.4) | 0.2016 | NA | NA |
The model was generated from a COX regression model that included age, gene mutation of DNMT3A, and RUNX1, FLT3-ITD, MT-CYB, WT1, IDH2, NPM1, IDH1, and expression level of STAB1. CI, confidence interval; HR, hazard ratio; NA, not available.