Table 3.
Reisolation of the challenge strain from piglets after intravenous challenge with S. suis cps9 strain 16085/3b.
| Immunization antigen | Number of piglets positive for the isolation of the challenge strain in an inner organb or in serosa or in joint fluid | Number of piglets positive for the isolation of the challenge strain in ≥ 3 inner organsb | Number of piglets in which the S.suis challenge straina was isolated from |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Tonsils | Lungc | Serosad | Spleen | Liver | Brain, CSFe | Joint fluidf | Endocard | |||
| placebo | 8/9 | 7/9 | 0/9 | 5/9 | 4/9 | 7/9 | 5/9 | 7/9 | 6/9 | 6/9 |
| rIdeSsuis | 1/9 | 0/9 | 0/9 | 0/9 | 0/9 | 0/9 | 1/9 | 0/9 | 0/9 | 1/9 |
a
The challenge strain was identified by PCR.
b
Inner organ refers to lung, spleen, liver, brain, CSF or endocard but not the tonsils.
c
One cranial lobe was investigated.
d
Pleural, peritoneal or pericardial cavity.
e
Cerebrospinal fluid.
f
Punctures of both tarsal and carpal joints were investigated in each animal. In case of lameness additional joint punctures of the respective limb were screened.