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. 2019 Nov 5;11:1759720X19885559. doi: 10.1177/1759720X19885559

Table 4.

Discriminatory performance of LUPHAS score compared with qSOFA score and CURB-65 score by receiver operating characteristic (ROC) curve analysis.

Model AUROC (CI 95%) Sensitivity Specificity
Total population (n = 130)
 LUPHAS 0.86 (0.79–0.92) 79.2% 80.5%
 qSOFA 0.69 (0.59–0.78) 64.0% 67.5%
Subgroup of lung infection (n = 108)
 LUPHAS 0.84 (0.76–0.92) 78.0% 79.4%
 CURB-65 0.69 (0.59–0.80) 39.5% 87.7%

The quick Sequential Organ Failure Assessment (qSOFA) score ranges 0–3 points, with 1 point each for systolic hypotension (⩽100 mm Hg), tachypnea (⩾22/min), or altered mentation. Patients with a score ⩾2 are associated with a greater risk of death or prolonged intensive care unit stay.

CURB-65 is a validated clinical assessment tool for predicting mortality in patients with community-acquired pneumonia, including confusion, urea >7 mmol/l, respiratory rate >30/min, low blood pressure (systolic <90 mm Hg, or diastolic <60 mm Hg, or both) and age ⩾65. Patients with a score ⩾2 are associated with a higher mortality and hospitalization needs to be considered.

AUROC, area under receiver operating characteristic curve; qSOFA, the quick Sequential Organ Failure Assessment.