Table 4.
Discriminatory performance of LUPHAS score compared with qSOFA score and CURB-65 score by receiver operating characteristic (ROC) curve analysis.
Model | AUROC (CI 95%) | Sensitivity | Specificity |
---|---|---|---|
Total population (n = 130) | |||
LUPHAS | 0.86 (0.79–0.92) | 79.2% | 80.5% |
qSOFA | 0.69 (0.59–0.78) | 64.0% | 67.5% |
Subgroup of lung infection (n = 108) | |||
LUPHAS | 0.84 (0.76–0.92) | 78.0% | 79.4% |
CURB-65 | 0.69 (0.59–0.80) | 39.5% | 87.7% |
The quick Sequential Organ Failure Assessment (qSOFA) score ranges 0–3 points, with 1 point each for systolic hypotension (⩽100 mm Hg), tachypnea (⩾22/min), or altered mentation. Patients with a score ⩾2 are associated with a greater risk of death or prolonged intensive care unit stay.
CURB-65 is a validated clinical assessment tool for predicting mortality in patients with community-acquired pneumonia, including confusion, urea >7 mmol/l, respiratory rate >30/min, low blood pressure (systolic <90 mm Hg, or diastolic <60 mm Hg, or both) and age ⩾65. Patients with a score ⩾2 are associated with a higher mortality and hospitalization needs to be considered.
AUROC, area under receiver operating characteristic curve; qSOFA, the quick Sequential Organ Failure Assessment.