Table 2.

Sex-specific characteristics of patients commencing kidney replacement therapy in historic cohorts

Characteristics	1965–1974			1975–1984			1985–1994			1995–2004			2005–2015
	Men	Women	P value	Men	Women	P value	Men	Women	P value	Men	Women	P value	Men	Women	P value
Age at onset (mean [SD])	39 (13)	38 (13)	0.12	47 (16)	48 (16)	0.0004	54 (17)	56 (17)	<0.001	61 (16)	62 (16)	<0.001	64 (16)	65 (16)	<0.001
Primary kidney disease (%)
Glomerulonephritis	57	41	<0.001	34	21	<0.001	23	15	<0.001	15	11	<0.001	11	9	<0.001
Pyelonephritis	10	25		12	23		10	15		7	9		5	6
Polycystic kidney disease	3	4		6	9		6	8		6	7		5	7
Hypertension	3	1		5	3		8	5		11	8		12	10
Diabetes mellitus	0.6	0.4		9	8		15	16		21	23		24	24
Kidney vascular disease	2	2		2	1		5	3		7	5		7	5
Miscellaneous	22	24		16	21		14	19		14	17		14	17
Unknown	3	3		15	14		18	18		19	19		20	21
First KRT modality (%)
HD	89	87	0.41	86	85	0.21	80	79	0.02	83	83	0.46	83	83	0.006
PD	9	10		12	13		18	9		15	15		13	13
Kidney transplantation	2	3		2	2		2	2		2	2		4	5
Country (%)
Austria	21	20	0.51	22	22	0.004	16	17	<0.001	15	15	<0.001	14	13	<0.001
Finland	16	17		12	12		6	7		7	6		6	5
Greece				11	10		17	16		22	21		25	25
Iceland	0.5	0.7		0.3	0.4		0.3	0.3		0.2	0.3		0.3	0.3
Norway				6	7		7	5		6	5		6	5
Andalusia				3	3		10	11		11	12		11	11
Catalonia				3	3		14	12		13	12		12	11
The Netherlands	50	51		34	36		23	24		21	21		21	22
UK (Scotland)	12	11		9	8		7	7		7	8		6	7

Totals may be not add up to 100% due to rounding. KRT, kidney replacement therapy; HD, hemodialysis; PD, peritoneal dialysis.