Figure 8. Structural ensembles of the complete sfRNAs.

• A–C
  The fitting chi‐square is plotted against the ensemble size for complete sfRNAs of DENV2 (A), ZIKV (B), and WNV (C), suggesting optimized minimal structural ensembles with 3, 3,3 conformers, respectively. The respective insets show the distribution of the minimal ensembles and the initial pools of 10,000 random conformers as a function of Rg.
• D–F
  The models of the selected minimal structural ensembles (N _e = 3) that can reproduce the scattering curves of the complete sfRNAs of DENV2 (D), ZIKV (E), and WNV (F) are shown. In each panel, the left are the three individual models in each ensemble overlaid on top of the DB1 domains, the right are the three individual models in each ensemble displayed separately. The xrRNA1, xrRNA2, SL3 of WNV, ψ‐DB1 and DB1, DB2, and 3′SL domains are colored in red, blue, cyan, green, magenta, and orange, respectively.