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. 2019 Oct 12;24(20):3675. doi: 10.3390/molecules24203675

Figure 2.

Figure 2

Activity of stilbene disulfonic acid derivatives against the ST activity of clinical RAL-resistant IN mutants. (A) Representative PAGE images showing NSC34931 inhibition of ST in the context of WT, Y143R, G140S/Q148H, and N155H RAL-resistant HIV-1 mutant integrases. (B–D) Quantitative analysis of the inhibition of ST by RAL, NSC34931, and NSC34933 derived from the densitometric analysis of gel-based experiments (including gels presented in panel A). Fitting curves and error bars represent the mean±SD from 10, 6, and 7 independent experiments for RAL, NSC34931, and NSC34933, respectively.