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Inhibition of the disintegration reaction by NSC34931. (A) Schematic representation of the disintegration reaction. The length of each oligonucleotide is indicated (nt = nucleotide) (B) Representative PAGE image of the inhibition of disintegration by NSC34931 on full-length IN (top) or the isolated catalytic core domain (bottom). (C) Densitometric analysis of the gel pictures presented in B. Data represent mean ± SD from at least three independent experiments.
