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. 2019 Oct 21;8(10):1750. doi: 10.3390/jcm8101750

Table 6.

Potential interventions in early- and late-onset neonatal sepsis prevention and control.

Implementation of Various BSI Prevention and Control Strategies References
Decrease of GBS in EOS:
● maternal intrapartum antibiotic prophylaxis
● GBS maternal vaccination (future solution)

[50,51,52,53,54,55,104]
[59,105,106,107,108]
Decrease of E. coli in EOS:
● E. coli maternal vaccination (future solution)

[109]
Decrease of EOS:
● risk stratification of asymptomatic neonates for empirical use of antibiotics

[60,61,62,69,70]
Decrease of LOS:
● surveillance with “bundle of care” strategy
● probiotics

[83,84,85]
[92,93]