Figure 4.
Graphical presentation of significant correlations between the epithelial alarmin levels and clinical measures in patients with IPF. Notes: Panels showing correlation between: (A) IL-33 serum levels and time since diagnosis, (B) IL-33 serum levels and CPI score, (C) TSLP serum levels and time since diagnosis, (D) IL-33 EBC levels and time since diagnosis, (E) IL-25 EBC levels and FEV1, (F) TSLP EBC levels and age. IPF—idiopathic pulmonary fibrosis, EBC—exhaled breath condensate, IL-25—interleukin 25, IL-33—interleukin 33, TSLP—thymic stromal lymphopoietin, FEV1—forced expiratory volume in 1 second, CPI—composite physiologic index.