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. 2019 Oct 2;8(10):1590. doi: 10.3390/jcm8101590

Figure 6.

Figure 6

Changes in the epithelial alarmin levels in the EBC of patients with IPF before and after 12 months of antifibrotic therapy according to the antifibrotic agent used. Notes: Panels showing: (A) change in IL-25 EBC level in IPF patients treated with nintedanib; (B) change in IL-25 EBC level in IPF patients treated with pirfenidone; (C) change in IL-33 EBC level in IPF patients treated with nintedanib; (D) change in IL-33 EBC level in IPF patients treated with pirfenidone; (E) change in TSLP EBC level in IPF patients treated with nintedanib; (F) change in TSLP EBC level in IPF patients treated with pirfenidone; * p < 0.05, **** p < 0.0001. Abbreviations: EBC—exhaled breath condensate, IPF—idiopathic pulmonary fibrosis, IL-25—interleukin 25, IL-33—interleukin 33, TSLP—thymic stromal lymphopoietin.