Table 1.
Newborns diagnosed with congenital hypothyroidism by cord blood and heel-stick sampling for thyroid stimulating hormone levels.
| Patient No. | Gender | Cord TSH (mlU/L) | Cord free T4 (pmol/L) | Heel stick TSH (μU/mL) | Peripheral venous sample | Radiotracer uptake | Thyroid ultrasound | Etiology | |
|---|---|---|---|---|---|---|---|---|---|
| TSH | free T4 | ||||||||
| 1 | Female | 106.2 | - | 83 | 141.39 | 12.7 | RTU above the normal thyroid gland location | TG noted in the anatomical location | Ectopic |
| 2 | Female | 742.8 | - | 434 | 705.62 | 14 | RTU in the thyroid bed | Small-sized TG | Ectopic |
| 3 | Male | 52.8 | 8.7 | 36.3 | 97.48 | 12.3 | Focal increased RTU in the upper neck region | Absence of TG in the expected region | Ectopic |
| 4 | Female | 50.5 | 8.5 | 51.9 | NA | NA | - | - | Expired at 6 days of age |
| 5 | Female | 105.6 | - | 141.7 | 239.32 | 17.2 | RTU located at the tongue base | TG noted in its anatomical location | Ectopic |
| 6 | Female | 89.0 | - | 104 | 321.80 | 15.1 | RTU seen in the neck (calculate uptake 4.5%) | TG noted at the hyoid bone leve | Dyshormonogenesis |
| 7 | Male | 473.6 | - | 349 | 566.31 | 5.9 | RTU midline above the normal thyroid location | - | Ectopic |
Abbreviation: THS: thyroid stimulating hormone, NA: not available, RTU: radiotracer uptake, TG:thyroid gland