AUC | area under the plasma drug concentration-t curve |
BCRP | Breast Cancer Resistance Protein |
Cmax | Maximum plasma drug concentration |
CYPs | Cytochromes P450 |
DDI | Drug–drug interaction |
IC50 | The half maximal inhibitory concentration |
MDCK cells | Madin-Darby canine kidney cells |
MRPs | Multidrug resistance-associated protein |
OATP | Organic-anion-transporting polypeptide |
P-gp | P-glycoprotein |
SULTs | sulfotransferases |
UGT | UDP-glucuronosyltransferase |