Table 2.
Sphinganine (Sa) and sphingosine (So) concentrations as well as sphinganine to sphingosine ratio (Sa/So) in supernatants of calf small intestinal epithelial cells B treated with increasing concentrations of FB1 (0–200 µM; n = 4 independent experiments). a,b Superscripts indicate significant differences to cells incubated without FB1 (0 µM).
| FB1 (µM) | Sa (ng/mL) | So (ng/mL) | Sa/So |
|---|---|---|---|
| 0 | 0.21 ± 0.81 a | 1.40 ± 0.40 | 0.15 ± 0.02 a |
| 0.781 | 0.28 ± 0.10 a | 1.42 ± 0.33 | 0.20 ± 0.03 a |
| 1.563 | 0.53 ± 0.25 a | 1.70 ± 0.47 | 0.31 ± 0.06 a |
| 3.125 | 3.89 ± 1.51 a | 1.61 ± 0.25 | 2.36 ± 0.55 a |
| 6.25 | 15.60 ± 5.91 a | 1.53 ± 0.25 | 9.98 ± 2.20 b |
| 12.5 | 33.61 ± 13.29 a | 1.96 ± 0.64 | 16.96 ± 2.11 b |
| 25 | 44.57 ± 17.19 b | 2.36 ± 1.00 | 19.11 ± 1.71 b |
| 50 | 50.64 ± 25.01 b | 2.49 ± 1.11 | 20.08 ± 0.86 b |
| 100 | 53.57 ± 23.27 b | 2.29 ± 0.90 | 23.25 ± 1.15 b |
| 200 | 56.13 ± 26.26 b | 2.16 ± 0.83 | 25.58 ± 2.11 b |
| p-value | <0.0001 | 0.0462 | <0.0001 |