Table 1.
Characteristics of admissions for exacerbation of COPD from 2001 to 2015 in Spain.
| 2001–2003 | 2004–2006 | 2007–2009 | 2010–2012 | 2013–2015 | Total | p | ||
|---|---|---|---|---|---|---|---|---|
| Sex, n (%) | Male | 227,159 (84.77) | 244,122 (85.62) | 262,861 (85.39) | 243,934 (84.49) | 234,464 (83.05) | 1,212,540 (84.68) | <0.001 |
| Female | 40,815 (15.23) | 41,007 (14.38) | 44,968 (14.61) | 44,769 (15.51) | 47,836 (16.95) | 219,395 (15.32) | ||
| Age | Mean (SD) | 73.6 (9.85) | 74.24 (9.96) | 74.72 (10.25) | 75.24 (10.46) | 75.26 (10.71) | 74.63 (10.27) | <0.001 |
| Age groups in years, n (%) |
40–64 | 43,592 (16.27) | 45,053 (15.8) | 49,955 (16.23) | 45,997 (15.93) | 46,486 (16.47) | 231,083 (16.14) | <0.001 |
| 65–74 | 89,012 (33.22) | 86,832 (30.45) | 83,077 (26.99) | 71,382(24.73) | 70,830 (25.09) | 401,133 (28.01) | ||
| 75–84 | 103,098 (38.47) | 115,080 (40.36) | 125,418 (40.74) | 118,041 (40.89) | 109,007 (38.61) | 570,644 (39.85) | ||
| ≥85 | 32,272 (12.04) | 38,164 (13.38) | 49 379 (16.04) | 53,283 (18.46) | 55,977 (19.83) | 229,075 (16) | ||
| Charlson comorbidity index, n (%) | 1 | 144,016 (53.74) | 137,056 (48.07) | 135 531 (44.03) | 114,458 (39.65) | 105,536 (37.38) | 636,597 (44.46) | <0.001 |
| 2 | 72,471 (27.04) | 80,072 (28.08) | 86,132 (27.98) | 80,587 (27.91) | 77,274 (27.37) | 396,536 (27.69) | ||
| ≥3 | 51,487 (19.21) | 68,001 (23.85) | 86,166 (27.99) | 93,658 (32.44) | 99,490 (35.24) | 398,802 (27.85) | ||
| Pneumonia, n (%) | Yes | 47,426 (17.7) | 53,678 (18.83) | 58,416 (18.98) | 61,497 (21.3) | 66,808 (23.67) | 287,825 (20.1) | <0.001 |
| Ventilation type, n (%) | NV | 258,932 (96.63) | 272,759 (95.66) | 290,577 (94.4) | 265,526 (91.97) | 255,912 (90.65) | 1,343,706 (93.84) | <0.001 |
| NIV | 4881 (1.82) | 7776 (2.73) | 13,072 (4.25) | 19,789 (6.85) | 23,293 (8.25) | 68,811 (4.81) | ||
| IMV | 3716 (1.39) | 3747 (1.31) | 3216 (1.04) | 2346 (0.81) | 1904 (0.67) | 14,929 (1.04) | ||
| NIV + IMV | 445 (0.17) | 847 (0.3) | 964 (0.31) | 1042 (0.36) | 1191 (0.42) | 4489 (0.31) | ||
| Length of hospital stay | Mean (sd) | 9.57 (8.32) | 9.25 (7.94) | 8.88 (7.98) | 8.33 (7.63) | 8.04 (6.89) | 8.81 (7.79) | <0.001 |
| In-hospital mortality, n (%) | Yes | 18,436 (6.88) | 20,170 (7.07) | 21,289 (6.92) | 19,866 (6.88) | 18,667 (6.61) | 98,428 (6.87) | <0.001 |
NV: no ventilation. NIV: non-invasive ventilation. IMV: invasive ventilation.