Table 3.

Kynurenines and associated elements (enzymes, receptors) and members of the ECS present in astrocytes and involved in schizophrenia. The table also highlights the common points between the two systems.

Members and Features	References
Kynurenines and associated elements
KYNA	[137]
KAT II	[35]
α7nAChR 1	[138]
ECS
AEA, 2-AG	[122,123]
DAGL, MAGL	[139,140]
CB1R	[141]
Common points
Involved in the THC-induced enhanced glutamate release	[142]
Co-localized CB1R and α7nAChRs mRNA	[142]

¹ although other KYNA receptors are present in astrocytes (see Section 4.3.2.), α7nAChRs have been the most promising candidate for mediating the effects of KYNA associated with schizophrenia [61].