Figure 2.

Serp-1 dose- and schedule-dependently accelerates full-thickness wound healing in mice. (A–C) The full course of wound healing for mice with full-thickness wounds treated with saline alone (N = 13) or Serp-1 at a dose of (A) 2 μg/mouse (Serp-1 [2]; N = 6), (B) 1 μg/mouse (Serp-1 [1]; N = 7), or (C) 1 μg/mouse on days 0 and 3 (Serp-1 [1+1]; N = 5). Dotted horizontal cross lines indicate equivalent healing of Serp-1 mice on day 3 as is achieved by saline alone on day 7.