Table 1.
Characteristics of E. coli O157 cases by Shiga toxin genotype.
| stx1a2a (n = 439) | stx2a-only (n = 225) | stx2a2c (n = 190) | Other (n = 82) | Overall (n = 936) | |
|---|---|---|---|---|---|
| Age (years) | |||||
| Median (IQR) | 18.0 (5.00, 42.5) | 11.0 (4.00, 30.0) | 12.0 (4.00, 33.0) | 23.0 (8.00, 46.8) | 16.0 (5.00, 39.3) |
| Comorbidity | |||||
| Present | 50 (11.4%) | 26 (11.6%) | 18 (9.5%) | 7 (8.5%) | 101 (10.8%) |
| Absent | 350 (79.7%) | 184 (81.8%) | 158 (83.2%) | 69 (84.1%) | 761 (81.3%) |
| Missing | 39 (8.9%) | 15 (6.7%) | 14 (7.4%) | 6 (7.3%) | 74 (7.9%) |
| Outbreak-related | |||||
| Yes | 42 (9.6%) | 32 (14.2%) | 14 (7.4%) | 1 (1.2%) | 89 (9.5%) |
| No | 397 (90.4%) | 193 (85.8%) | 176 (92.6%) | 81 (98.8%) | 847 (90.5%) |
| Diarrhea | |||||
| Present | 433 (98.6%) | 221 (98.2%) | 187 (98.4%) | 81 (98.8%) | 922 (98.5%) |
| Absent | 2 (0.5%) | 3 (1.3%) | 1 (0.5%) | 0 (0%) | 6 (0.6%) |
| Missing | 4 (0.9%) | 1 (0.4%) | 2 (1.1%) | 1 (1.2%) | 8 (0.9%) |
| Blood in stool | |||||
| Present | 398 (90.7%) | 189 (84.0%) | 161 (84.7%) | 61 (74.4%) | 809 (86.4%) |
| Absent | 31 (7.1%) | 32 (14.2%) | 22 (11.6%) | 20 (24.4%) | 105 (11.2%) |
| Missing | 10 (2.3%) | 4 (1.8%) | 7 (3.7%) | 1 (1.2%) | 22 (2.4%) |
| Vomiting | |||||
| Present | 204 (46.5%) | 121 (53.8%) | 102 (53.7%) | 28 (34.1%) | 455 (48.6%) |
| Absent | 223 (50.8%) | 103 (45.8%) | 82 (43.2%) | 52 (63.4%) | 460 (49.1%) |
| Missing | 12 (2.7%) | 1 (0.4%) | 6 (3.2%) | 2 (2.4%) | 21 (2.2%) |
| Abdominal pain | |||||
| Present | 408 (92.9%) | 204 (90.7%) | 175 (92.1%) | 71 (86.6%) | 858 (91.7%) |
| Absent | 16 (3.6%) | 13 (5.8%) | 8 (4.2%) | 8 (9.8%) | 45 (4.8%) |
| Missing | 15 (3.4%) | 8 (3.6%) | 7 (3.7%) | 3 (3.7%) | 33 (3.5%) |
| Fever | |||||
| Present | 167 (38.0%) | 78 (34.7%) | 70 (36.8%) | 20 (24.4%) | 335 (35.8%) |
| Absent | 245 (55.8%) | 132 (58.7%) | 107 (56.3%) | 53 (64.6%) | 537 (57.4%) |
| Missing | 27 (6.2%) | 15 (6.7%) | 13 (6.8%) | 9 (11.0%) | 64 (6.8%) |
| Hospitalized | |||||
| Yes | 167 (38.0%) | 93 (41.3%) | 85 (44.7%) | 20 (24.4%) | 365 (39.0%) |
| No | 263 (59.9%) | 130 (57.8%) | 105 (55.3%) | 60 (73.2%) | 558 (59.6%) |
| Missing | 9 (2.1%) | 2 (0.9%) | 0 (0%) | 2 (2.4%) | 13 (1.4%) |
| HUS | |||||
| Yes | 28 (6.4%) | 24 (10.7%) | 16 (8.4%) | 1 (1.2%) | 69 (7.4%) |
| No | 411 (93.6%) | 201 (89.3%) | 174 (91.6%) | 81 (98.8%) | 867 (92.6%) |
| RRT | |||||
| Yes | 11 (2.5%) | 14 (6.2%) | 10 (5.3%) | 1 (1.2%) | 36 (3.8%) |
| No | 428 (97.5%) | 211 (93.8%) | 180 (94.7%) | 81 (98.8%) | 900 (96.2%) |
Patient or caregiver reported presence of fever; if temperature was reported, fever was defined as ≥38.0 °C. ‘Other’ genotype includes stx1a-only, stx1a2a2c, stx1a2c, and stx2c-only genotypes. Abbreviations: HUS, hemolytic uremic syndrome; IQR, interquartile range; RRT, renal replacement therapy.