Table 2.

Tac trough level and dose of two calcineurin inhibitor toxicity groups.

	x < 25% (n = 35)	x ≥ 25% (n = 20)	p-Value
Tac trough level (ng/mL ± SD)	6.0 (3.1–15.1)	5.8 (2.4–12.5)	0.431
Tac dose (mg, mean ± SD)	5.0 (1.0–18.0)	8.0 (3.0–16.0)	0.009
C/D ratio, ng/mL×1/mg, median (min-max)	1.27 (0.28–5.03)	0.78 (0.33–1.20)	< 0.001

Tac, tacrolimus; Mann–Whitney U test.