Table 3.
IC50 values exhibited by G. edulis methanol extract and methanol fractions against the inhibitory activity of the enzymes α-amylase and α-glucosidase and antiglycation activities.
| Extract/Fraction | Alpha-Amylase (µg/mL) |
Alpha-Glucosidase (µg/mL) |
Anti-Glycation (µg/mL) |
|---|---|---|---|
| Crude methanol extract | 349.59 ± 2.44 a | 102.24 ± 0.89 a | 702.33 ± 12.72 a |
| Hexane fraction | 393.04 ± 4.73 b | 163.90 ± 5.23 b | 637.53 ± 6.21 b |
| Chloroform fraction | 322.71 ± 4.80 c | 122.65 ± 2.37 c | 258.23 ± 3.24 c |
| Ethyl acetate fraction | 279.48 ± 5.62 d | 87.92 ± 1.62 d | 586.54 ± 4.37 b |
| Aqueous fraction | 376.49 ± 12.14 e | 148.57 ± 1.87 e | 723.78 ± 12.81 d |
| Acarbose (standard) | 87.43 ± 0.59 f | 0.38 ± 0.06 f | - |
| Rutin (standard) | - | - | 11.55 ± 0.82 e |
Results are expressed as mean ± SD (n = 4). *p < 0.05 compared with the respective standard. Mean values in a column superscripted by different letters (a–f) are significantly different at p < 0.05.