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Study design. The cats were first adapted and trained for blood and sample collection. At the age of 15 and 18 weeks, the cats were vaccinated subcutaneously (FCV (feline calicivirus) F9 or placebo vaccine). Seven months later (age of 46 weeks), all cats were challenged using the FCV 273 virus. Eleven months later (94 weeks of age), all cats were revaccinated once (FCV F9 or placebo vaccine) prior to the second FCV challenge with FCV 27 at 99 weeks of age.
