Table 1.
Summary of clinical and technical features of all included patients.
| Case | Sex | Age (years) | Pathology, Location, Strategy | Proximal Vessel Diameter in mm | Distal Vessel Diameter in mm | Implanted Device | Maximal Device Oversizing | Vasoconstricive Segmental Stenosis %; Location | Time Point of Follow-Up Imaging Post Implantation | Additional In-Stent Stenosis/Neointimal Hyperplasia | Cumulative Local Stenosis |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Male | 51 | Left V4, ruptured dissecting aneurysm, primary Flow Diverting Stent (FDS) |
4.2 | 2.5 | PED 2 400-300 | 1.5 mm, 60% | 15% distal landing zone (distal V4) | 20 weeks | 20% | 35% |
| 2 | Male | 72 | Basilar artery, ruptured blister aneurysm, primary FDS | 2.2 | 1.7 | p48 HPC 300-18 | 1.3 mm, 56% | 45% distal landing zone (basilar tip) | 8 weeks | Radiography only, not assessable | Minimum of 30% |
| 3 | Female | 51 | Left M1, ruptured saccular aneurysm, Plug and Pipe (P&P) | 2 | 1.4 | P48200-15 | 0.6 mm, 30% | 25% proximal landing zone (left M1) | 4 weeks | Radiography only, not assessable | Minimum of 30% |
| 4 * | Male | 64 | Left A1–A2, ruptured saccular aneurysm, P&P after pCONus 2 Stent-Assisted Coiling (SAC) |
2.1 | 1.7 | p48 HPC 300-18 | 1.3 mm, 43% | 12% distal landing zone (A2; uncovered by pCONus) | 5 weeks | Radiography only, not assessable | 12% |
| 5 * | Female | 78 | Right Middle Cerebral Artery (MCA) bifurcation, incidental saccular giant-aneurysm, elective P&P after pCONus 2 SAC |
3.0 | 2.6 | p48 HPC 300-18 | 0.4 mm, 13% | 31% distal landing zone (right M2, not covered by pCONus) | 5 weeks | Radiography only, not assessable | 31% |
| 6 # | Female | 52 | Basilar artery right P1, incidental saccular giant aneurysm, primary FDS | 2.7 | 2.1 | 2 × p48 HPC 300-18 | 0. 9 mm, 30% | 14% distal landing zone (right P1) | 5 weeks | Radiography only, not assessable | 14% |
| 7 | Male | 33 | Right A1, incidental saccular aneurysm, primary FDS |
1.9 | 2.4 | p48 HPC 300-15 | 1.1 mm, 42% | 37% proximal landing zone (right A1) | 5 weeks | Radiography only, not assessable | Minimum of 37% |
| 8 | Female | 49 | Left PcomA-ostium, ruptured saccular aneurysm, P&P |
2.5 | 3.1 | p64 300-15 | 0.5m, 20% | 20% proximal landing zone (ICA) | 14 weeks | 10% | 30% |
| 9 | Male | 37 | Right M1, incidental saccular aneurysm, elective P&P | 2.6 | 2.4 | PED2-275-12 | 0.35 mm, 15% | 33% distal landing zone (M2) and 15% proximal landing zone (M1) | 10 weeks | 10% | 43% |
| 10 | Male | 51 | Left A1–A2, incidental saccular aneurysm, primary FDS | 1.8 | 1.8 | SVB 2.25 × 15 | 0.45 mm, 25% | 33% proximal landing zone (A1) | 13 weeks | 20% | 53% |
| 11 | Female | 18 | Right M2, incidental saccular aneurysm, primary FDS | 1.8 | 1.9 | SVB 2.25 × 15 | 0.45 mm, 25% | 19% proximal landing zone (M2) | 12 weeks | 22% | 41% |
| 12 | Female | 39 | Left A1–A2,ruptured saccular aneurysm, P&P | 1.8 | 1.8 | SVB 2.25 × 20 | 0.45 mm, 25% | 42% proximal landing zone (A1) | 14 weeks | 5% | 47% |
| 13 | Female | 50 | Right A2–A3, incidental saccular aneurysm, primary FDS | 1.8 | 1.7 | SVB 2.25 × 10 | 0.55 mm, 32% | 33% proximal landing zone (A2) | 17 weeks | 10% | 43% |
| 14 * | Female | 38 | Left A1–A2, incidental saccular aneurysm, primary FDS | 1.7 | 2.0 | SVB 2.25 × 10; 2.25 × 15 | 0.55 mm, 32% | 18% proximal landing zone (A1) | 28 weeks | 13% | 31 % |
| 15 | Female | 55 | Right A1/2, ruptured saccular aneurysm, P&P | 1.7 | 1.6 | SVB 2.25 × 15 | 0.65 mm, 40% | 56% proximal landing zone (A1) | 17 weeks | 10% | 66% |
| 16 | Female | 48 | Left PICA, ruptured saccular aneurysm, P&P | 2.4 | 2.3 | SVB 2.25 × 10 | none | None | 14 weeks | 10% | 10% |
| 17 * | Male | 55 | Right A1–A2, incidental aneurysm, primary FDS | 2.0 | 1.9 | SVB 2.25 × 15 | 0.35 mm, 18% | 33% proximal landing zones (each) | 14 weeks | 0% | 33% |
| 18 | Female | 40 | A1–A2, ruptured saccular aneurysm, P&P | 2.2 | 1.7 | SVB 2.25 × 15 | 0.55 mm, 32% | 33% of the proximal and distal landing zones (A1, A2) | 9 weeks | 10% | 43% |
| 19 | Female | 59 | Left paraophthalmic Internal Carotid Artery (ICA), incidental saccular aneurysm, primary FDS | 3.4 | 3.0 | SVB 3.25 × 20 | 0.25 mm, 8% | 17% distal landing zone (ICA) | 12 weeks | 0% | 17% |
| 20 | Female | 70 | Right Posterior Communicating Artery (PcomA), incidental saccular aneurysm, primary FDS | 3.1 | 3.0 | SVB 3.25 × 25 | none | None | 12 weeks | 0% | 0% |
| 21 | Female | 56 | Left Posterior Inferior Cerebellar Artery (PICA), ruptured saccular aneurysm, P&P | 3.4 | 3.2 | SVB 3.25 × 10 | 0.05 mm, 1.5% | None | 12 weeks | 0% | 0% |
| 22 | Female | 39 | Right A1–A2, ruptured saccular aneurysm, P&P | 2.0 | 1.7 | SVB 2.25 × 15 | 0.55 mm, 25% | 25% proximal landing zone (A1) | 16 weeks | 10% | 35% |
| 23 | Female | 58 | Left A1–A2, ruptured saccular aneurysm, P&P | 2.3 | 2.1 | SVB 2.25 × 15 | 0.1 mm, 7% | None | 15 weeks | 0% | 0% |
| 24 * | Female | 58 | Left RCP and left MCA, incidental saccular aneurysm, primary FDS | 3.4 | 1.6 | SVB 3.25 × 20; 3.25 × 25 | 1.6 mm, 51 % | Distal landing zone 25% M1 | 14 weeks | 10% | 35% |
| 25 # | Female | 64 | Right A2–A3, saccular aneurysm, elective P&P after Leo-Baby + coiling | 1.8 | 1.7 (covered by LEO baby stent) | SVB 2.25 × 10 | 0.55 mm, 32% | Proximal landing zone 13% (A2) | 19 weeks | 15% | 28% |
| 26 | Male | 38 | Left ICA bifurcation + RCP, ruptured saccular aneurysm, P&P + primary FDS | 3.6 | 2.5 | SVB 3.25 × 20 | 0.75 mm, 30% | 40% distal landing zone (M1) 30% middle–proximal quarter (ICA) |
13 weeks | 5% | 45% |
| 27 | Female | 27 | Left M1, ruptured saccular aneurysm, P&P | 3.5 | 2.8 | SVB 3.25 × 20 | 0.45 mm, 16% | >85% of the proximal (ICA) and >60% of the distal landing zone (M1) | 3 weeks | 10% | >95% |
| 28 | Male | 63 | Left A1–A2, incidental saccular aneurysm, primary FDS | 2.2 | 1.8 | SVB 2.25 × 15 | 0.45 mm, 25% | 38% of the distal (A2) and 27% of the proximal landing zone (A1) | 16 weeks | 0% | 38% |
| 29 | Male | 52 | Left supraophthalmic ICA, ruptured saccular aneurysm, P&P | 3.2 | 2.9 | SVB 3.25 × 25 | 0.35 mm, 12% | 7% distal landing zone | 8 weeks | 0% | 7% |
| 30 | Male | 40 | Left PICA, ruptured saccular aneurysm, P&P | 2.5 | 2.5 | SVB 2.75 × 25 | 0.25 mm, 10% | 42% proximal landing zone | 6 weeks | 67% | 81% |
| 31 * | Male | 60 | Right M1, ruptured saccular aneurysm, P&P | 3.1 | 2.8 | SVB 2.25 × 15; 2.75 × 15 | none | 0% | 5 weeks | 0% | 0% |
| 32 | Male | 54 | Left A1–A2, ruptured saccular aneurysm, P&P | 2.5 | 1.8 | SVB 2.75 × 20 | 0,95 mm, 52% | 48% proximal landing zone (A1) 44% distal landing zone (A2) | 6 weeks | Radiography only, not assessable | 48% |
| 33 | Female | 55 | Right A1–A2, ruptured saccular aneurysm, P&P | 2.1 | 1.5 | SVB 2.25 × 20 | 0,75 mm, 50% | 33% distal landing zone (A2) 20% proximal landing zone (A1) | 7 weeks | Radiography only, not assessable | 33% |
| 34 | Female | 61 | Right A1–A2, ruptured saccular aneurysm, P&P | 2.0 | 1.9 | SVB 2.25 × 15 | 0,35 mm, 15% | 50% distal landing zone 20% proximal landing zone | 5 weeks | Radiography only, not assessable | 50% |
| 35 | Male | 35 | Left A1–A2, incidental saccular aneurysm, primary FDS | 3.0 | 2.5 | p48 3 × 18 | 0.5 mm, 20% | 53% distal landing zone, 40% proximal landing zone | 4 weeks | 0% | 53% |
| 36 | Male | 36 | Left V4, incidental saccular aneurysm, primary FDS | 3.1 | 2.5 | SVB 2.75 × 25 | 0.25 mm, 10% | 72% proximal landing zone | 5 weeks | 10% | 82% |
* Patients treated with FDS implantation within a previously implanted aneurysm stent. # Patients treated with 2 FDS simultaneously–telescoping.