Table 3.
Apelin and apelin receptor tissue level in CRC patients. Tissue level of apelin and APJ was normalized to non-tumour tissue, and analyzed using the Wilcoxon test. * Statistically significant at p < 0.05.
| Variable | Non-Tumour tissue. mean ± SD median (min–max) |
Tumour tissue. mean ± SD median (min–max) |
Tumour/non-Tumour ratio mean ± SD median (min–max) |
p-Value |
|---|---|---|---|---|
| Apelin (ng/g of tissue) | 36.00 ± 17.33 34.27 (6.05–101.6) |
48.91 ± 18.30 47.77 (4.24–113.37) |
1.68 ± 1.37 1.4 (0.21–8.44) |
<0.0001 * |
| Apelin receptor (μg/g of tissue) | 10.34 ± 13.07 5.29 (0.19–54.7) |
32.32 ± 20.20 31.46 (1.11–72.35) |
7.98 ± 9.59 5.58 (0.2–53.52) |
<0.0001 * |