Table 1.
Patient characteristics, significance level: p < 0.05.
| HTx (n = 112) | HI (n = 89) | p-Value | ||
|---|---|---|---|---|
| Gender (female in % (n)) | 23.2% (26) | 15.7% (4) | 0.22 | |
| Age in years (mv ± sd) | 56.15 ± 12.23 | 55.47 ± 10.91 | 0.57 | |
| Time since HTx in years (mv ± sd) | 7.1 ± 5.50 | - | - | |
| Smoking habits % (n) | smoker | 5.4% (6) | 17% (15) | 0.02 |
| nonsmoker | 74.1% (83) | 60.3% (54) | ||
| former smoker | 20.5% (23) | 22.7% (20) | ||
| Ejection fraction in % (mv ± sd) | 57.31 ± 8.04 | 28.17 ± 9.36 | <0.01 | |
| Underlying heart disease % (n) | DCM | 61.6% (69) | 61.8% (55) | 0.99 |
| ICM | 31.3% (35) | 32.6% (29) | 0.88 | |
| valvular insufficiency | 13.4% (15) | 38.2% (34) | <0.01 | |
| atrial fibrillation | 6.3% (7) | 29.2% (26) | <0.01 | |
| Co-morbidities % (n) | hypertension | 55.9% (62) | 74.2% (66) | 0.01 |
| diabetes mellitus | 34.8% (39) | 36% (32) | 0.88 | |
| osteoporosis | 5.4% (6) | 4.5% (4) | 0.99 | |
| renal insufficiency | 84.8% (95) | 44.9% (40) | <0.01 | |
| adipositas | 51.8% (58) | 42.7% (38) | 0.21 | |
| Medication relevant to oral conditions % (n) | calcium-channel blocker | 25.2% (28) | 5.7% (5) | <0.01 |
| immunosuppression | 100% (112) | 5.7% (5) | <0.01 | |
| bisphopshonates | 31.8% (35) | 4.6% (4) | <0.01 | |
| Blood parameters (mv ± sd) (at the time of evaluation) | CRP (mg/L) | 5.40 ± 10.49 | 11.65 ± 23.57 | 0.03 |
| creatinine (µmol/L) | 45.88 ± 111.78 | 45.95 ± 73.68 | 0.67 | |
| hemoglobin (mmol/ L) | 8.55 ± 1.88 | 8.23 ± 1.76 | 0.68 | |
| erythrocytes (106/µ L) | 4.53 ± 0.62 | 4.61 ± 0.74 | 0.56 | |
| leukocytes (10³/µ L) | 6.50 ± 1.90 | 7.79 ± 2.76 | 0.01 | |
| platelet (10³/µ L) | 214.73 ± 77.88 | 237.93 ± 76.33 | 0.07 | |
| NYHA class | I | - | 5% (4/76) | - |
| I–II | 5% (4/76) | |||
| II | 47% (36/76) | |||
| II–III | 5% (4/76) | |||
| III | 26% (4/76) | |||
| III–IV | 5% (4/76) | |||
| IV | 5% (4/76) | |||
HTx: heart transplantation, HI: heart insufficiency, CRP: c-reactive protein, mv: mean value, sd: standard deviation, DCM: dilatative cardio-myopathy, ICM: ischeamic cardio-myopathy; significant values (p < 0.05) are highlighted in bold.