Figure 4.
Icariin administration for 30 days ameliorated the indexes of spleen (A), thymus (B), and uterine (C) in perimenopausal depression rats. Values are expressed as mean ± S.D, n = 10. ## p < 0.01 versus the SG. ** p < 0.01 versus the MG. * p < 0.05 versus the MG. Sham group (SG), model group (MG), estradiol valerate group (EVG, 0.167 mg/kg), high-dose icariin group (IG-HD, 50 mg/kg), medium-dose icariin group (IG-MD, 25 mg/kg), low-dose icariin group (IG-LD, 12.5 mg/kg). Values are expressed as mean ± S.D, n = 10. ## p < 0.01 versus the SG. ** p < 0.01 versus the MG. * p < 0.05 versus the MG. (Statistical analyses were performed using ANOVA, and the criterion for statistical significance was set to p < 0.05).