Table 1.

Chronic unpredictable mild stress (CUMS) procedure.

Stressor	Details
Food deprivation	Rats were subjected to 24 h of food deprivation. Food was provided immediately after the end of the fasting period.
Water deprivation	Rats were subjected to 24 h of water deprivation. Water was provided immediately after the end of the fasting period.
Overnight illumination	Lights on for 24 h starting 20:30
Wet sawdust bedding	1 mL of water per 1 g of sawdust bedding for 20 h. Immediately after the stress, rats were removed from the cage and towel dried before being placed back in their home cage.
Heat environment	45 °C for 5 min
Cold water swimming	Rats were placed for 5 min in a cylindrical clear plastic tank (46 cm high (H) × 20 cm diameter (D) filled with water (4 ± 1 °C) to a depth of 30 cm. Immediately after the swim, rats were removed from the tank and towel dried before being placed back in their home cage.