Figure 7.
Effect of obatoclax, emetine and their combinations on influenza A virus (FLUAV)-mediated GFP expression and the viability of mock- and virus-infected RPE cells. (A,B) RPE cells were treated with increasing concentrations of a compound and infected with FLUAV-GFP (moi, 0.5). After 24 h, the cells were imaged and fluorescence intensity was quantified (Mean ± SD; n = 3). (C) Cell viability was determined with the CTG assay (Mean ± SD; n = 3). (D–E) The interaction landscapes of the emetine-obatoclax drug combination on FLUAV-mediated GFP expression and the viability of FLUAV- and mock-infected RPE cells, as measured with CTG assay.