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. 2019 Oct 7;8(10):1640. doi: 10.3390/jcm8101640

Table 3.

Add-on treatments for antidepressant-induced anorgasmia [77,78,79,80,81,82,83,84].

Drug Mechanism of Action Dose (mg/day)
Ciproheptadine 5HT antagonism 4–8
Buspirone 5HT1A partial agonism 14–45
Yohimbine α-2 adrenergic antagonism 5–10
Amantadine Dopaminergic agonist 100–400
Metilphenidate Dopaminergic agonist 10–30
Bupropion Dopaminergic and adrenergic effect 150–300
Mirtazapine 5HT2 antagonism 15–45