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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Cornea. 2019 Dec;38(12):1500–1505. doi: 10.1097/ICO.0000000000002147

Table 5:

Previous studies on the prevalence of novel autoantibodies in dry eye patients with or without Sjogren syndrome

Sjogren Syndrome Non-Sjogren Syndrome
Study N Any SP-1 PSP CA-6 N Any SP-1 PSP CA-6
Current Study 81 43% 21% 35% 15% 129 36% 12% 21% 20%
Karakus et al (J Immunol Res 2019) 11 primary SS 73% 27% 54% 27% 97 38% 13% 10% 22%
7 secondary SS 14% 14% 0 0
Bunya DREAM (Cornea 2018) 52 46% 33% 14% 21% 352 31% 19% 9% 15%
Karakus et al (Cornea 2018) 46 13% 11% 52% 14% 14% 43%
Everett et al (BMC Ophthalmol 2017) 62 60%
Matossian (Clin Ophthalmol 2016) 41 21%
Shen et al (Clin Immunol 2014) 123 52%
Shen et al (Clin Immunol 2012) 13 54% 18% 54%