Table 2:

Correlates of Mycoplasma genitalium infection from random sample (n=220) of HIV-seropositive pregnant women.

Characteristic	N	Women without M. genitalium infection (N=173) Mean (SD) or N (%)	Women with M. genitalium infection (N=47) Mean (SD) or N (%)	p-value*
*Baseline (32 weeks gestation)*
Age (years)	220	25 (4.4)	25 (3.7)	0.70
Education (years)	218	8.8 (2.7)	8.9 (2.9)	0.86
Single	220	7 (4.1%)	5 (10.6%)	0.08
Employed	220	127 (73.4%)	33 (70.2%)	0.66
Age at first intercourse (years)	220	17.4 (2.4)	17.3 (2.5)	0.81
Lifetime sexual partners	220	3 (1.6)	3 (1.5)	0.86
Parity	217	1.5 (1.3)	1.6 (1.3)	0.69
History of tuberculosis	220	15 (8.7%)	1 (2.1%)	0.13
History of syphilis	220	18 (10.4%)	2 (4.3%)	0.19
History of any sexually transmitted infection (STI)	220	26 (15%)	2 (4.3%)	0.05
History of genital ulcer disease	220	13 (7.5%)	0	0.05
HSV-2 positive	137	91 (87.5%)	30 (91%)	0.60
CD4 count (cells/mm³)	216	479 (236)	522 (258)	0.29
Plasma HIV RNA (log₁₀ copies/ml)	210	4.6 (0.92)	5.0 (0.73)	0.02
*Pregnancy*
Diagnosed with tuberculosis	219	2 (1.2%)	0	0.46
Diagnosed with syphilis	217	6 (3.5%)	1 (2.1%)	0.63
Diagnosed with genital ulcers	219	7 (4.1%)	2 (4.3%)	0.96
Diagnosed with BV	209	61 (37%)	19 (43.2%)	0.45
Diagnosed with trichomoniasis	220	28 (16.2%)	13 (27.7%)	0.07
Diagnosed with gonorrhea	219	2 (1.2%)	0	0.46
Diagnosed with chlamydia	219	8 (4.7%)	2 (4.3%)	0.91
*Delivery*
Plasma HIV RNA (log₁₀ copies/ml)	169	4.0 (1.0)	4.3 (0.78)	0.16
Vaginal HIV RNA (log₁₀ copies/ml)	150	2.4 (1.1)	2.6 (1)	0.45

Chi squared test or Fisher’s exact test were used to compare categorical variables; t-tests were used to compare continuous variables. HIV RNA testing of plasma (n=169) and vaginal swabs (n=150) was not available at delivery for all mothers; similarly HSV-2 testing was not available for all mothers (n=137).