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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: J Immunol. 2019 Oct 9;203(10):2571–2576. doi: 10.4049/jimmunol.1900426

Figure 1. Neonatal CD8+ T cells exhibit higher glycolytic metabolism after in vitro stimulation.

Figure 1.

(A) OCR measurements of adult and neonatal CD8+ T cells at 48hr after α-CD3 and α-CD28 activation. (B) Basal OCR, (C) Basal ECAR, and (D) Basal OCR/ECAR ratios in adult and neonatal CD8+ T cells at 48hr after α-CD3 and α-CD28 activation. (E) Pathway of critical proteins in glycolysis. (F) Fold change in mRNA expression of proteins 8 hours post-stimulation using qPCR. Data representative of two independent experiments with 3–5 biological replicates/group. * p<0.05, ** p<0.005 by unpaired student t-test.