Figure 2. Neonatal CD8+ T cells possess an inherent propensity to undergo glycolytic metabolism following infection.
(A) The experimental design to examine the metabolic programs of neonatal and adult CD8+ T cells during infection. (B) Representative contour plots of KLRG1 and CD127 expression at 7 dpi (C) OCR measurements, (D) Basal and max OCR, and (E) SRC values in adult and neonatal CD8+ T cells during a Mitochondrial Stress Test at 7 dpi (F) ECAR measurements and (G) Basal and max ECAR values of adult and neonatal CD8+ T cells during a Glycolysis Stress Test at 7 dpi. Data representative of 2 independent experiments with three biological replicates/group. ** p<0.005, *** p<0.0005 by unpaired student t-test.