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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: J Immunol. 2019 Oct 9;203(10):2571–2576. doi: 10.4049/jimmunol.1900426

Figure 3. Lin28b drives a more glycolytic metabolic program in CD8+ T cells.

Figure 3.

(A) The experimental design to examine the metabolic programs of WT adult and Lin28b Tg adult CD8+ T cells during infection. (B) Representative contour plot of KLRG1 and CD127 expression at 7 dpi (C) OCR measurements, (D) Basal and max OCR, (E) SRC values in adult and neonatal CD8+ T cells at 7 dpi from a mitochondrial stress test (F) ECAR measurements, (G) Basal and max ECAR values in WT and Lin28b tg CD8+ T cells from a glycolysis stress test at 7 dpi. Data representative of 2 independent experiments with 3 biological replicates/group. * p<0.05, ** p<0.005 by unpaired student t-test