. 2019 Sep 23;8(10):1524. doi: 10.3390/jcm8101524

Table 3.

Differentially abundant transcripts observed in both cohorts.

Compartment	Transcript	Toronto Cohort	Longitudinal Cohort
Compartment	Transcript	Toronto Cohort	Complete Responders	Non-Responders
Glomerular	FN1	Positive correlation with the degree of endocapillary hypercellularity	Decreased with response	Increased
	LGALS3	Positive correlation with degree of crescent formation	Trend towards decrease with response	No change
	SPP1	Positive correlation with the degree of endocapillary hypercellularity	Decreased with response	No change
Tubulointerstitial	IL1RL1	Decreased level in patients with interstitial fibrosis	No Change	No change
Tubulointerstitial	TLR4	Decreased level in patients with interstitial fibrosis	No Change	No Change

The abundance of glomerular FN1, LGALS3, and SPP1 RNA was concordant in both cohorts and reflective of activity. All five genes were interferon-regulated.