(A) SAW sensor response as measured IL-6 mass (fg/mL) vs. applied IL-6 mass (µg/mL), the sensor surface was modified following IL-6 immobilization through BSA. (B) SAW sensor response as measured IL-6 mass (fg/mL) vs. applied IL-6 mass (µg/mL), the sensor surface follows specific IL-6 binding through immobilization of IL-6 monoclonal antibodies. In both figures two windows of 5 × 5 µm2 and 20 × 20 µm2 were tested, sensor measurements indicated that by increasing the active surface area of the device, the sensor response increases as shown by 20 × 20 µm2 window in both cases, adapted with permission from [154].