Table 1.
Patient characteristics.
| Demographic Characteristics | |
|---|---|
| Sex ratio M/F | 0.8 (4/5) |
| Age | |
| Mean ± standard deviation | 14.4 (±3.7) |
| Median | 16.5 |
| Weight | |
| Mean ± standard deviation | 49.9 (±20.5) |
| Median | 49.1 |
| Background (Number of Patients and Percentage) | |
| Cholecystectomy | 3 (33%) |
| Stroke | 1 (11.1%) |
| Abnormal Transcranial doppler episode | 1 (11.1%) |
| Osteonecrosis | 2 (22.2%) |
| Retinopathy | 1 (11.1%) |
| Splenic Sequestration | 0 (0%) |
| Pulmonary Hypertension | 1 (11.1%) |
| Cardiac Events | 1 (11.1%) |
| Kidney Failure | 0 (0%) |
| Events per Year: 2016–2018 Period | |
| Transfusion/Year | |
| Mean ± Standard Deviation | 0.8 |
| Median | 0.3 (0–2) |
| Hospitalization/Year | |
| Mean ± standard deviation | 1.4 |
| Median (range) | 0.6 (0–5.0) |
| VOC/Year | |
| Mean ± Standard Deviation | 1.6 |
| Median (range) | 1 (0–5.6) |
| ACS | |
| Number of Patients > 1 ACS | 4 (45%) |
| HU | |
| Dose (mg/kg/day) | |
| Mean ± Standard Deviation | 19.0 (±4.0) |
| Median (range) | 20.4 (12.9–24.6) |
| Time since Introduction of HU (Months) | |
| Mean ± Standard Deviation | 63.5 (±44.6) |
| Median (Range) | 58.8 (11.2–138.8) |
| Age at Introduction (Year) | |
| Mean ± Standard Deviation | 8.5 (±4.4) |
| Median (Range) | 6.0 (4.0–16.0) |
HU: Hydroxyurea; VOC: vaso-occlusive crisis; ACS: acute chest syndrome. M: male; F: female.