Table 1.
Demographic, clinical, and histological information of patients with NP lymphoma.
| Case Number (n = 35) | ||
|---|---|---|
| Age | 17–88 (mean 59.57 ± 18.84) | |
| Sex | M/F = 20/15 | |
| Symptoms | ||
| Nasal obstruction | 10 (28.6%) | |
| Epistaxis | 9 (25.7%) | |
| Neck mass | 8 (22.9%) | |
| Purulent Rhinorrhea | 6 (17.1%) | |
| Headache | 5 (14.3%) | |
| B symptoms | 5 (14.3%) | |
| Symptom Duration | 0.5–12 (mean 2.61 ± 2.97) | |
| Location of Disease | ||
| NP only | 22 (62.9%) | |
| NP + neck/distant LN * | 10 (28.6%) | |
| NP + adjacent organ # | 3 (8.6%) | |
| Comorbidity | ||
| HTN | 10 (28.6%) | |
| DM | 6 (17.1%) | |
| CAD | 4 (11.4%) | |
| Lab | ||
| WBC | 2400–167800 (mean 12992) | |
| LDH | 106–1702 (mean 337.7) | |
| EBER | ||
| Positive | 13 (37.1%) | |
| Negative | 19 (54.3%) | |
| NA | 3 (8.6%) | |
| Stage (Ann Arbor) | ||
| I | 12 (34.3%) | |
| II | 15 (42.9%) | |
| IV | 8 (22.9%) | |
| Treatment | ||
| CT | 20 (57.1%) | |
| RT | 1 (2.9%) | |
| CT+RT | 6 (17.1%) | |
| CT+PBSCT | 5 (14.3%) | |
| CT+RT+PBSCT | 2 (5.7%) | |
| No treatment | 1 (2.9%) | |
| Recurrence | 8 (22.9%) | |
| Dead | 19 (54.3%) | |
# sinonasal cavity, oropharynx, hypopharynx; *gastrointestinal (GI) tract, inguinal lymph node (LN), neck LN. Abbreviation: CT: chemotherapy; RT: radiotherapy; PBSCT: peripheral blood stem cell transplantation; EBER: Epstein–Barr virus-encoded small RNAs; NA: not available; HTN: hypertension; DM: Diabetes mellitus; CAD: Coronary artery disease; WBC: white blood cell count; LDH: lactic dehydrogenase.