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. 2019 Nov 6;20:551. doi: 10.1186/s12859-019-3134-5

Fig. 4.

Fig. 4

The riboflavin biosynthetic pathway. The gene names are written in italic, while the iSM996 reaction IDs are written in red colour. Abbreviations for metabolites: GTP (guanosine-5′-triphosphate), 5a65prau (5-amino-6-(5-phosphoribitylamino)uracil), 5a6Drau (5-amino-6-(D-ribitylamino) uracil, D-ribul 5-P (D-ribulose 5-phosphate), 2h3obp (2-hydroxy-3-oxobutyl phosphate), 67dm81Drl (6,7-dimethyl-8-(1-D-ribityl) lumazine production). Abbreviations for genes: KmRIB3 (3,4-dihydroxy-2-butanone-4-phosphate synthase), KmRIB4 (lumazine synthase), KmRIB5 (riboflavin synthase), KmFMN1 (riboflavin kinase), KmFAD1 (FAD synthetase), KmLTP1 (putative protein phosphotyrosine phosphatase), KmNPP1 (nucleotide pyrophosphatase/phosphodiesterase)