Table 2.

PH Cox regression univariate analyses for the association of gene SPAG5 with endocrine therapy and chemotherapy

	RFS			OS			DMFS
	n	HR	P-value	n	HR	P-value	n	HR	P-value
Systemic therapy subtypes
Endo	849	1.57 (1.2–2.06)	0.001	128	2 (1.05–3.8)	0.03	513	2.36 (1.57–3.54)	< 0.001
Tamoxifen-only	739	1.57 (1.17–2.12)	0.0027	114	2.13 (1–4.52)	0.044	556	2.23 (1.52–3.26)	< 0.001
Chemo	274	1.1 (0.74–1.63)	0.64	69	1.54 (0.74–3.2)	0.25	65	1.49 (0.65–3.4)	0.34
Endo + chemo	171	2.77 (1.37–5.6)	0.0032	34	4.28 (0.48–38.33)	0.16	86	1.96 (0.66–5.86)	0.22

Endo Endocrine therapy, chemo Chemotherapy