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. 2019 Nov 6;19:296. doi: 10.1186/s12906-019-2679-1

Table 6.

Percent AChE and BChE inhibition potential of pyrogallol, morin and rutin isolated from Bergenia ciliata rhizome

Samples Concentrations (μg/mL) AChE percent inhibition (mean ± S.E.M) AChE IC50 (μg/mL) BChE percent inhibition (mean ± S.E.M) BChE IC50 (μg/mL)
Pyrogallol 1000 94.35 ± 0.72 ns 92.02 ± 1.89 ns
500 87.40 ± 1.51 ns 80.35 ± 0.30 *
250 80.12 ± 0.62 ns 28 71.18 ± 1.38 ns 70
125 66.24 ± 2.14 ns 58.28 ± 0.93 ns
Morin 1000 85.51 ± 3.19*** 80.46 ± 0.76***
500 77.23 ± 0.91*** 68.44 ± 2.22***
250 68.82 ± 0.80 *** 64 60.51 ± 0.50*** 116
125 56.33 ± 1.45 *** 51.13 ± 0.56***
Rutin 1000 75.11 ± 1.41*** 72.05 ± 0.86***
500 66.72 ± 0.62*** 62.47 ± 1.72***
250 60.20 ± 2.35*** 118 56.68 ± 0.70*** 172
125 48.09 ± 0.64*** 45.00 ± 3.79***
Galanthamine 1000 97.24 ± 0.74 92.26 ± 0.92
500 90.43 ± 0.50 86.51 ± 0.77
250 79.00 ± 0.65 24 71.80 ± 0.48 54
125 66.07 ± 1.46 62.43 ± 0.39

Galanthamine was used as a positive control. Data is represented as (mean ± S.E.M) n = 3. Values significantly different as compared to positive control, *: P < 0.05, **: P < 0.01, ***: P < 0.001, ns: P > 0.05