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. 2019 Nov 5;19:271. doi: 10.1186/s12883-019-1460-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Brain MRI T1-weighted imaging without (c) and with (d) gadolinium contrast enhancement. Hydrocephalus as a consequence of disease progression. Hyper-intensity on T1 was due to the paramagnetic effect of melanin, which had stable organic free radicals inside it, resulting in shortened T1 relaxation times in typical melanotic melanoma