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. 2019 Oct 16;16(159):20190356. doi: 10.1098/rsif.2019.0356

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© 2019 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 11. — Reducing biomarker abnormality through delayed conversion. Decreasing the conversion α delays the accumulation of the misfolded protein concentration c and with it the biomarker abnormality $C$ . Irrespective of the conversion rate α, the misfolded protein concentration of the Fisher–Kolmogorov model always converges towards the fully misfolded state with a biomarker abnormality of $C = 100 %$ . (Online version in colour.)