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. 2019 Oct 16;16(159):20190356. doi: 10.1098/rsif.2019.0356

Figure 15.

Figure 15.

Reducing biomarker abnormality through increased clearance. Increasing the clearance k~1 delays and reduces the accumulation of misfolded tau protein p~ and with it the biomarker abnormality P~. Depending on the clearance rate k~1, the misfolded protein concentration of the Heterodimer model can converge towards intermediate states with a reduced biomarker abnormality of P~<100%. (Online version in colour.)