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. 2019 Sep 10;15:7–13. doi: 10.1016/j.eclinm.2019.08.015

Table 1.

Study characteristics of the 17 with low risk of bias overall.

Author, year Country, language Population Procedures Prediction technique Time to postoperative lung function Sample analysed (total) Outcomes Analysis
Fourdrain et al., 2017 [11] France, English N = 23 82.6% male Mean age 61 Lobectomy & Pneumonectomy Segment counting Subsegment counting Perfusion scintigraphy Ventilation scintigraphy CT partial density & volume 3 months 23 (37) FEV1 Mean difference Correlation
Yabuuchi, 2016[12] Japan, English N = 49 53.1% male Mean age 67 Lobectomy Subsegment counting CT volumetry CT volume & density 6–7 months 49 (49) FEV1 Change only Mean difference Correlation
Ohno, 2015[13] Japan, English N = 60 65.0% male Mean age 68 Segmentectomy, lobectomy & bilobectomy Segment counting Perfusion scintigraphy CT volume & density MRI perfusion 6 months 60 (60) FEV1 % only Mean difference Correlation
Chae, 2013[14] Korea, English N = 51 74.5% male Mean age 64 Lobectomy & pneumonectomy Perfusion scintigraphy CT perfusion 6 months 51 (67) FEV1 Mean difference Correlation
Yanagita, 2013[15] Japan, English N = 30 63.3% male Mean age 70 Lobectomy & pneumonectomy SPECT CT ventilation 6 months 30 (34) FEV1 Mean difference Correlation
Yamashita, 2010[16] Canada, English N = 14 60.0% male Mean age 65 Lobectomy & pneumonectomy Perfusion scintigraphy CT perfusion 3 months 14 (25) FEV1 Mean difference Correlation
Yoshimoto, 2009[17] Japan, English N = 37 59.4% male Mean age 65 Lobectomy Segment counting CT volume & density SPECT–CT 3 months 37 (37) FEV1 Mean difference Correlation
Ohno, 2007[18] Japan, English N = 60 50.0% male Mean age 70 Lobectomy & pneumonectomy Perfusion scintigraphy Ventilation scintigraphy SPECT SPECT–CT 6 months 60 (60) FEV1 % only Mean difference Correlation
Sudoh, 2006[19] Japan, English N = 22 86.4% male Mean age 71 Lobectomy & segmentectomy Subsegment counting SPECT–CT 3–4 months 22 (22) FEV1 Correlation
Wang, 2006[20] Canada, English N = 28 61.0% male Mean age 65 Segmentectomy, lobectomy & pneumonectomy Segment counting 12 months 28 (57) DLCO % only Mean difference
Wu, 2002[21] Taiwan, English N = 34 79.5% male Mean age 67 Lobectomy & pneumonectomy Perfusion scintigraphy CT volume & density 3 months 34(52) FEV1 Mean difference Correlation
Beccaria, 2001[22] Italy, English N = 62 82.3% male Mean age 62 Lobectomy & pneumonectomy Segment counting 6 months 62 (93) FEV1 Correlation
Larsen, 1997[23] Denmark, English N = 23 65.2% male Mean age 67 Lobectomy & pneumonectomy Perfusion scintigraphy 6 months 23 (41) FEV1 Mean difference
Bolliger, 1995[24] Switzerland, English N = 22 68.0% male Mean age 63 Wedge resection, segmentectomy, lobectomy & pneumonectomy Perfusion scintigraphy 6 months 22 (25) FEV1 & DLCO Correlation
Wu, 1994[25] China, English N = 38 86.8% male Mean age 68 Lobectomy & pneumonectomy CT volume & density 3 months 38 (38) FEV1 Mean difference Correlation
Egeblad, 1986[26] Denmark, English N = 30 70.8% male Mean age 61 Lobectomy & pneumonectomy Segment counting 6 months 30 (30) FEV1 Correlation
Taube, 1980[27] Germany, German N = 27 100% male Mean age 53 Pneumonectomy Perfusion scintigraphy 6 months 27 (29) FEV1 Correlation