AD	Alzheimer’s disease
AFD	allele frequency difference statistic [97]
CAD	coronary artery disease
DD	Dupuytren’s disease
EMOD	Early- to Middle-age-Onset polygenic Disease
Fst	F-statistics, originally conceived as te fixation index by Wright, implemented here using Hudson’s method [96]
GRS	genetic risk score; used synonymously with polygenic risk score, abbreviated below
GWAS	genome-wide association study
LE	lupus erythematosus
LOD	late-onset disease; herein, analyzed LODs are exclusively polygenic
MAF	minor allele frequency; customarily implies the effect allele frequency
OR	odds ratio
PRS	polygenic risk score; in this study, a normalized sum of logarithms of additional relative risk conferred by causal alleles
RA	rheumatoid arthritis
RR	relative risk or risk ratio
SNP	single nucleotide polymorphism; in the context of this study, SNP is used synonymously with the term ’allele’
T2D	type 2 diabetes
WGS	whole genome sequencing ff