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. 2019 Oct 9;20(20):4998. doi: 10.3390/ijms20204998

Scheme 2.

Scheme 2

Conversion of PAMAM G3 dendrimer to G3gl by hydroxyalkylation with glycidol. PAMAM G3 has 32 terminal amine groups (n = 32) that each react with two molecules of gl to give a total of 64 2,3-dihydroxypropyl substituents with 128 free hydroxyl groups.