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Effect of ZD7288 on the mitochondrial respiration rate and mitochondrial membrane potential (ΔΨm) on isolated mitochondria from renal cortex. (a) Respiratory parameters: state 2 (S2), state 3 (S3) and state 4 induced by oligomycin (S4o) and (b) respiratory control index (RCI). (c) Δψm in S2, S3 and S4o. Data are mean ± SEM, n = 5. *** p < 0.001, ** p < 0.01 and * p < 0.05.
