Fig 3. Estimated doubling times and precursor frequencies for HIV Gag-specific CD8 T cell growth after PD-L1 Blockade.

Analysis of donor 82 data under the assumption of equal precursor frequencies (%), assumption 1 of Fig 1(A) or equal turnover rates, assumption 2 of Fig 1(B). The estimated increase of the CD8 T cell precursor frequency under assumption 2 for all five analysed blood donors is shown in (C). Iso, isotype control; block, PD-L1 blockade.